TY - GEN AU - Fu,Dong-Jun AU - Fu,Ling AU - Liu,Ying-Chao AU - Wang,Jun-Wei AU - Wang,Yu-Qing AU - Han,Bing-Kai AU - Li,Xiao-Rui AU - Zhang,Chuang AU - Li,Feng AU - Song,Jian AU - Zhao,Bing AU - Mao,Ruo-Wang AU - Zhao,Ruo-Han AU - Zhang,Sai-Yang AU - Zhang,Li AU - Zhang,Yan-Bing AU - Liu,Hong-Min TI - Structure-Activity Relationship Studies of β-Lactam-azide Analogues as Orally Active Antitumor Agents Targeting the Tubulin Colchicine Site SN - 2045-2322 PY - 2019///0625 KW - Administration, Oral KW - Animals KW - Antineoplastic Agents KW - administration & dosage KW - Apoptosis KW - drug effects KW - Azides KW - Cadherins KW - metabolism KW - Cell Line, Tumor KW - Cell Movement KW - Colchicine KW - chemistry KW - Down-Regulation KW - Humans KW - Inhibitory Concentration 50 KW - Mice, Inbred BALB C KW - Mice, Nude KW - Structure-Activity Relationship KW - Tubulin KW - Up-Regulation KW - Zonula Occludens-1 Protein KW - beta-Lactams N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/s41598-017-12912-4 ER -