Hughes, James <br/><br/>
Knockout of the epilepsy gene Depdc5 in mice causes severe embryonic dysmorphology with hyperactivity of mTORC1 signalling.  [electronic resource] 

 -  Scientific reports  10 2017 
 - 12618 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>2045-2322 
<br/><br/><label>Standard No.: </label>10.1038/s41598-017-12574-2  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Brain--physiopathology<br/>CRISPR-Cas Systems--genetics<br/>Disease Models, Animal<br/>Epilepsy--genetics<br/>Fibroblasts--pathology<br/>GTPase-Activating Proteins--genetics<br/>Gene Expression Regulation<br/>Heterozygote<br/>Humans<br/>Mechanistic Target of Rapamycin Complex 1--genetics<br/>Mice<br/>Mice, Knockout<br/>Multiprotein Complexes--chemistry<br/>Mutation<br/>Seizures--genetics<br/>Signal Transduction--genetics