TY - GEN AU - Brady,Lauren K AU - Wang,Hejia AU - Radens,Caleb M AU - Bi,Yue AU - Radovich,Milan AU - Maity,Amit AU - Ivan,Cristina AU - Ivan,Mircea AU - Barash,Yoseph AU - Koumenis,Constantinos TI - Transcriptome analysis of hypoxic cancer cells uncovers intron retention in EIF2B5 as a mechanism to inhibit translation SN - 1545-7885 PY - 2017///1030 KW - Alternative Splicing KW - genetics KW - Base Sequence KW - Cell Line, Tumor KW - Eukaryotic Initiation Factor-2B KW - Gene Expression Profiling KW - methods KW - Gene Expression Regulation, Neoplastic KW - Genetic Loci KW - Head and Neck Neoplasms KW - Humans KW - Introns KW - Models, Biological KW - Nucleotide Motifs KW - Phosphorylation KW - Polymerase Chain Reaction KW - Protein Binding KW - Protein Biosynthesis KW - Protein Isoforms KW - RNA Polymerase II KW - metabolism KW - RNA, Messenger KW - Regulatory Sequences, Nucleic Acid KW - Reproducibility of Results KW - Tumor Hypoxia N1 - Publication Type: Journal Article UR - https://doi.org/10.1371/journal.pbio.2002623 ER -