TY - GEN AU - Shu,Xing-Sheng AU - Zhao,Yingying AU - Sun,Yanmei AU - Zhong,Lan AU - Cheng,Yingduan AU - Zhang,Yixiang AU - Ning,Kaile AU - Tao,Qian AU - Wang,Yejun AU - Ying,Ying TI - The epigenetic modifier PBRM1 restricts the basal activity of the innate immune system by repressing retinoic acid-inducible gene-I-like receptor signalling and is a potential prognostic biomarker for colon cancer SN - 1096-9896 PY - 2018///0109 KW - Aged KW - Biomarkers KW - metabolism KW - Colonic Neoplasms KW - diagnosis KW - DEAD Box Protein 58 KW - genetics KW - DNA-Binding Proteins KW - Epigenomics KW - Female KW - Humans KW - Immunity, Innate KW - Inflammatory Bowel Diseases KW - complications KW - Interferon-Induced Helicase, IFIH1 KW - Male KW - Nuclear Proteins KW - Prognosis KW - RNA, Small Interfering KW - Receptors, Immunologic KW - Sequence Analysis, RNA KW - Signal Transduction KW - Transcription Factors KW - Tretinoin KW - Tripartite Motif Proteins KW - Ubiquitin-Protein Ligases KW - Ubiquitination N1 - Publication Type: Journal Article UR - https://doi.org/10.1002/path.4986 ER -