Anzovino, Amy

Molecular Alterations in a Mouse Cardiac Model of Friedreich Ataxia: An Impaired Nrf2 Response Mediated via Upregulation of Keap1 and Activation of the Gsk3β Axis. [electronic resource] - The American journal of pathology Dec 2017 - 2858-2875 p. digital

Publication Type: Journal Article

1525-2191

10.1016/j.ajpath.2017.08.021 doi


Animals
Cardiomyopathies--genetics
Disease Models, Animal
Friedreich Ataxia--genetics
Glycogen Synthase Kinase 3 beta--metabolism
Iron-Binding Proteins--genetics
Kelch-Like ECH-Associated Protein 1--metabolism
Mice
Mice, Inbred C57BL
Mice, Knockout
Muscle, Skeletal--metabolism
Myocardium--metabolism
NF-E2-Related Factor 2--metabolism
Oxidative Stress--physiology
Up-Regulation
Frataxin