Li, Qi

20(S)-Ginsenoside Rh2 suppresses proliferation and migration of hepatocellular carcinoma cells by targeting EZH2 to regulate CDKN2A-2B gene cluster transcription. [electronic resource] - European journal of pharmacology Nov 2017 - 173-180 p. digital

Publication Type: Journal Article

1879-0712

10.1016/j.ejphar.2017.09.023 doi


Animals
Carcinoma, Hepatocellular--drug therapy
Cell Line, Tumor
Cell Movement--drug effects
Cell Proliferation--drug effects
Cyclin-Dependent Kinase Inhibitor p15--genetics
Cyclin-Dependent Kinase Inhibitor p16--genetics
Down-Regulation--drug effects
Enhancer of Zeste Homolog 2 Protein--metabolism
G1 Phase Cell Cycle Checkpoints--drug effects
Ginsenosides--pharmacology
Humans
Liver Neoplasms--drug therapy
Male
Mice
Molecular Targeted Therapy
Multigene Family--genetics
Promoter Regions, Genetic--genetics
RNA, Messenger--genetics
Resting Phase, Cell Cycle--drug effects
Transcription, Genetic--drug effects
Xenograft Model Antitumor Assays