TY  - GEN
AU  - Mould,Daniel P
AU  - Bremberg,Ulf
AU  - Jordan,Allan M
AU  - Geitmann,Matthis
AU  - McGonagle,Alison E
AU  - Somervaille,Tim C P
AU  - Spencer,Gary J
AU  - Ogilvie,Donald J
TI  - Development and evaluation of 4-(pyrrolidin-3-yl)benzonitrile derivatives as inhibitors of lysine specific demethylase 1
SN  - 1464-3405
PY  - 2017///1103
KW  - Binding Sites
KW  - Cell Line, Tumor
KW  - Drug Design
KW  - Enzyme Activation
KW  - drug effects
KW  - Enzyme Inhibitors
KW  - chemical synthesis
KW  - Histone Demethylases
KW  - antagonists & inhibitors
KW  - Humans
KW  - Inhibitory Concentration 50
KW  - Molecular Docking Simulation
KW  - Nitriles
KW  - Protein Structure, Tertiary
KW  - Pyrrolidines
KW  - chemistry
KW  - Stereoisomerism
KW  - Structure-Activity Relationship
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.bmcl.2017.08.052
ER  -