Mould, Daniel P <br/><br/>
Development and evaluation of 4-(pyrrolidin-3-yl)benzonitrile derivatives as inhibitors of lysine specific demethylase 1.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  10 2017 
 - 4755-4759 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1464-3405 
<br/><br/><label>Standard No.: </label>10.1016/j.bmcl.2017.08.052  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Binding Sites<br/>Cell Line, Tumor<br/>Drug Design<br/>Enzyme Activation--drug effects<br/>Enzyme Inhibitors--chemical synthesis<br/>Histone Demethylases--antagonists & inhibitors<br/>Humans<br/>Inhibitory Concentration 50<br/>Molecular Docking Simulation<br/>Nitriles--chemical synthesis<br/>Protein Structure, Tertiary<br/>Pyrrolidines--chemistry<br/>Stereoisomerism<br/>Structure-Activity Relationship