TY - GEN AU - Sun,Xun AU - Dyson,H Jane AU - Wright,Peter E TI - Fluorotryptophan Incorporation Modulates the Structure and Stability of Transthyretin in a Site-Specific Manner SN - 1520-4995 PY - 2017///1024 KW - Amino Acid Substitution KW - Dimerization KW - Fluorescent Dyes KW - chemistry KW - Kinetics KW - Models, Molecular KW - Mutation KW - Nuclear Magnetic Resonance, Biomolecular KW - Prealbumin KW - Protein Aggregation, Pathological KW - genetics KW - Protein Conformation KW - Protein Denaturation KW - drug effects KW - Protein Interaction Domains and Motifs KW - Protein Multimerization KW - Protein Stability KW - Protein Unfolding KW - Recombinant Proteins KW - Tryptophan KW - analogs & derivatives KW - Urea N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1021/acs.biochem.7b00815 ER -