TY - GEN AU - Mould,Daniel P AU - Alli,Cristina AU - Bremberg,Ulf AU - Cartic,Sharon AU - Jordan,Allan M AU - Geitmann,Matthis AU - Maiques-Diaz,Alba AU - McGonagle,Alison E AU - Somervaille,Tim C P AU - Spencer,Gary J AU - Turlais,Fabrice AU - Ogilvie,Donald TI - Development of (4-Cyanophenyl)glycine Derivatives as Reversible Inhibitors of Lysine Specific Demethylase 1 SN - 1520-4804 PY - 2017///1030 KW - Antineoplastic Agents KW - chemical synthesis KW - Biomarkers KW - Cell Line, Tumor KW - Computer Simulation KW - Drug Design KW - Drug Discovery KW - Enzyme Inhibitors KW - Ether-A-Go-Go Potassium Channels KW - drug effects KW - Glycine KW - analogs & derivatives KW - High-Throughput Screening Assays KW - Histone Demethylases KW - antagonists & inhibitors KW - Humans KW - Leukemia KW - drug therapy KW - Models, Molecular KW - Molecular Docking Simulation KW - Spiro Compounds KW - Structure-Activity Relationship KW - Tranylcypromine N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1021/acs.jmedchem.7b00462 ER -