Loss of PRP4K drives anoikis resistance in part by dysregulation of epidermal growth factor receptor endosomal trafficking. [electronic resource]
- Oncogene 01 2018
- 174-184 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1476-5594
10.1038/onc.2017.318 doi
Animals Anoikis--genetics Biomarkers, Tumor--deficiency Breast Neoplasms--pathology Cell Line, Tumor Cell Nucleus--metabolism Down-Regulation Endosomes--metabolism Epidermal Growth Factor--metabolism Epithelial Cells--cytology ErbB Receptors--metabolism Female Humans Lung Neoplasms--pathology Mice Mice, Inbred C57BL Neoplasm Invasiveness--pathology Ovarian Neoplasms--pathology Protein Serine-Threonine Kinases--deficiency RNA, Small Interfering--metabolism Ribonucleoprotein, U4-U6 Small Nuclear--deficiency Signal Transduction--genetics Xenograft Model Antitumor Assays Zebrafish