TY  - GEN
AU  - Wang,Huanchen
AU  - Shears,Stephen B
TI  - Structural features of human inositol phosphate multikinase rationalize its inositol phosphate kinase and phosphoinositide 3-kinase activities
SN  - 1083-351X
PY  - 2017///1121
KW  - Amino Acid Sequence
KW  - Amino Acid Substitution
KW  - Binding Sites
KW  - Carbohydrate Conformation
KW  - Catalytic Domain
KW  - Conserved Sequence
KW  - Crystallography, X-Ray
KW  - Humans
KW  - Inositol 1,4,5-Trisphosphate
KW  - chemistry
KW  - Inositol Phosphates
KW  - Models, Molecular
KW  - Mutagenesis, Site-Directed
KW  - Mutation
KW  - Phosphotransferases (Alcohol Group Acceptor)
KW  - Protein Conformation
KW  - Protein Interaction Domains and Motifs
KW  - Protein Structure, Secondary
KW  - Recombinant Proteins
KW  - Sequence Alignment
KW  - Substrate Specificity
N1  - Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Intramural
UR  - https://doi.org/10.1074/jbc.M117.801845
ER  -