TY - GEN AU - Barzegar,Mansoureh AU - Ma,Shuang AU - Zhang,Chao AU - Chen,Xin AU - Gu,Ying AU - Shang,Chaowei AU - Jiang,Xiaojuan AU - Yang,Jiao AU - Nathan,Cherie-Ann AU - Yang,Shengyong AU - Huang,Shile TI - SKLB188 inhibits the growth of head and neck squamous cell carcinoma by suppressing EGFR signalling SN - 1532-1827 PY - 2017///1023 KW - Animals KW - Apoptosis KW - drug effects KW - Blotting, Western KW - Carcinoma, Squamous Cell KW - metabolism KW - Cell Proliferation KW - Cyclin A KW - Cyclin D1 KW - Cyclin-Dependent Kinase 2 KW - Cyclin-Dependent Kinase 4 KW - Cyclin-Dependent Kinase Inhibitor p21 KW - Cyclin-Dependent Kinase Inhibitor p27 KW - Down-Regulation KW - ErbB Receptors KW - antagonists & inhibitors KW - G1 Phase Cell Cycle Checkpoints KW - Head and Neck Neoplasms KW - Humans KW - Immunohistochemistry KW - In Situ Nick-End Labeling KW - In Vitro Techniques KW - Mice KW - Mice, Nude KW - Molecular Docking Simulation KW - Purines KW - pharmacology KW - Signal Transduction KW - Squamous Cell Carcinoma of Head and Neck KW - Up-Regulation KW - Xenograft Model Antitumor Assays KW - cdc25 Phosphatases N1 - Publication Type: Journal Article UR - https://doi.org/10.1038/bjc.2017.298 ER -