TY  - GEN
AU  - Chen,Ming-Liang
AU  - Zhu,Xiao-Hui
AU  - Ran,Li
AU  - Lang,He-Dong
AU  - Yi,Long
AU  - Mi,Man-Tian
TI  - Trimethylamine-N-Oxide Induces Vascular Inflammation by Activating the NLRP3 Inflammasome Through the SIRT3-SOD2-mtROS Signaling Pathway
SN  - 2047-9980
PY  - 2018///0521
KW  - Animals
KW  - Antioxidants
KW  - pharmacology
KW  - Apoptosis Regulatory Proteins
KW  - metabolism
KW  - Atherosclerosis
KW  - chemically induced
KW  - Cells, Cultured
KW  - Disease Models, Animal
KW  - Dose-Response Relationship, Drug
KW  - Female
KW  - Genetic Predisposition to Disease
KW  - Human Umbilical Vein Endothelial Cells
KW  - drug effects
KW  - Humans
KW  - Inflammasomes
KW  - agonists
KW  - Inflammation Mediators
KW  - Methylamines
KW  - toxicity
KW  - Mice, 129 Strain
KW  - Mice, Knockout, ApoE
KW  - Mitochondria
KW  - NLR Family, Pyrin Domain-Containing 3 Protein
KW  - Phenotype
KW  - RNA Interference
KW  - Reactive Oxygen Species
KW  - Signal Transduction
KW  - Sirtuin 3
KW  - deficiency
KW  - Superoxide Dismutase
KW  - Time Factors
KW  - Transfection
KW  - Vasculitis
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1161/JAHA.117.006347
ER  -