TY - GEN AU - Toyama,Tetsuo AU - Looney,Agnieszka P AU - Baker,Brendon M AU - Stawski,Lukasz AU - Haines,Paul AU - Simms,Robert AU - Szymaniak,Aleksander D AU - Varelas,Xaralabos AU - Trojanowska,Maria TI - Therapeutic Targeting of TAZ and YAP by Dimethyl Fumarate in Systemic Sclerosis Fibrosis SN - 1523-1747 PY - 2019///0325 KW - Adaptor Proteins, Signal Transducing KW - metabolism KW - Adult KW - Animals KW - Biopsy KW - Bleomycin KW - toxicity KW - Cell Cycle Proteins KW - Cell Nucleus KW - Cells, Cultured KW - Dimethyl Fumarate KW - pharmacology KW - Disease Models, Animal KW - Female KW - Fibroblasts KW - Fibrosis KW - Humans KW - Intracellular Signaling Peptides and Proteins KW - Male KW - Mice KW - Mice, Inbred C57BL KW - Middle Aged KW - Phosphatidylinositol 3-Kinase KW - Phosphoproteins KW - Proteolysis KW - drug effects KW - Proto-Oncogene Proteins c-akt KW - Scleroderma, Systemic KW - drug therapy KW - Signal Transduction KW - Skin KW - Trans-Activators KW - Transcription Factors KW - Transcriptional Coactivator with PDZ-Binding Motif Proteins KW - Transforming Growth Factor beta KW - Treatment Outcome KW - YAP-Signaling Proteins N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1016/j.jid.2017.08.024 ER -