Yamamoto, Naoki Epigallocatechin gallate induces extracellular degradation of amyloid β-protein by increasing neprilysin secretion from astrocytes through activation of ERK and PI3K pathways. [electronic resource] - Neuroscience Oct 2017 - 70-78 p. digital Publication Type: Journal Article ISSN: 1873-7544 Standard No.: 10.1016/j.neuroscience.2017.08.030 doi Subjects--Topical Terms: Amyloid beta-Peptides--metabolismAnimalsAstrocytes--drug effectsCatechin--analogs & derivativesCell Membrane--drug effectsCells, CulturedCerebral Cortex--drug effectsDose-Response Relationship, DrugExtracellular Signal-Regulated MAP Kinases--metabolismExtracellular Space--drug effectsIsoflavones--pharmacologyNeprilysin--metabolismNeuroprotective Agents--pharmacologyPhosphatidylinositol 3-Kinases--metabolismProteolysis--drug effectsRats, Sprague-Dawley