Hashwah, Hind

Inactivation of CREBBP expands the germinal center B cell compartment, down-regulates MHCII expression and promotes DLBCL growth. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America 09 2017 - 9701-9706 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1091-6490

10.1073/pnas.1619555114 doi


Animals
B-Lymphocytes--immunology
CREB-Binding Protein--antagonists & inhibitors
CRISPR-Cas Systems
Cell Line, Tumor
Cell Proliferation--genetics
Down-Regulation
E1A-Associated p300 Protein--antagonists & inhibitors
Gene Deletion
Genes, MHC Class II
Germinal Center--immunology
HLA Antigens--genetics
Heterografts
Histone Code--genetics
Humans
Lymphoma, Large B-Cell, Diffuse--genetics
Mice
Mice, Inbred C57BL
Mice, Knockout
Mutation
Tumor Suppressor Proteins--antagonists & inhibitors