TY - GEN AU - Moreno-Smith,Myrthala AU - Lakoma,Anna AU - Chen,Zaowen AU - Tao,Ling AU - Scorsone,Kathleen A AU - Schild,Linda AU - Aviles-Padilla,Kevin AU - Nikzad,Rana AU - Zhang,Yankai AU - Chakraborty,Rikhia AU - Molenaar,Jan J AU - Vasudevan,Sanjeev A AU - Sheehan,Vivien AU - Kim,Eugene S AU - Paust,Silke AU - Shohet,Jason M AU - Barbieri,Eveline TI - p53 Nongenotoxic Activation and mTORC1 Inhibition Lead to Effective Combination for Neuroblastoma Therapy SN - 1557-3265 PY - 2018///0723 KW - Animals KW - Antineoplastic Combined Chemotherapy Protocols KW - administration & dosage KW - Apoptosis KW - drug effects KW - Cell Line, Tumor KW - Cell Proliferation KW - Drug Resistance, Neoplasm KW - genetics KW - Gene Expression Regulation, Neoplastic KW - Humans KW - Mechanistic Target of Rapamycin Complex 1 KW - antagonists & inhibitors KW - Mice KW - Neuroblastoma KW - drug therapy KW - Proto-Oncogene Proteins c-mdm2 KW - Pyrrolidines KW - Sirolimus KW - TOR Serine-Threonine Kinases KW - Tumor Suppressor Protein p53 KW - Xenograft Model Antitumor Assays KW - para-Aminobenzoates N1 - Publication Type: Journal Article UR - https://doi.org/10.1158/1078-0432.CCR-17-0668 ER -