Boiteau, Jean-Guy <br/><br/>
Discovery and process development of a novel TACE inhibitor for the topical treatment of psoriasis.  [electronic resource] 

 -  Bioorganic & medicinal chemistry  02 2018 
 - 945-956 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1464-3391 
<br/><br/><label>Standard No.: </label>10.1016/j.bmc.2017.07.054  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>ADAM17 Protein--antagonists & inhibitors<br/>Administration, Topical<br/>Animals<br/>Drug Design<br/>Enzyme Inhibitors--chemical synthesis<br/>Female<br/>Humans<br/>Hydroxamic Acids--chemistry<br/>Mice<br/>Mice, Hairless<br/>Microsomes, Liver--metabolism<br/>Oxazolone--toxicity<br/>Psoriasis--drug therapy<br/>Skin Diseases--chemically induced<br/>Solubility<br/>Sulfonamides--chemical synthesis<br/>Tumor Necrosis Factor-alpha--antagonists & inhibitors