Schiff base derived from thiosemicarbazone and anthracene showed high potential in overcoming multidrug resistance in vitro with low drug resistance index. [electronic resource]
- Drug design, development and therapy 2017
- 2227-2237 p. digital
Publication Type: Journal Article
1177-8881
10.2147/DDDT.S138371 doi
Anthracenes--chemistry Antineoplastic Agents--chemistry Apoptosis--drug effects Breast Neoplasms--drug therapy Cell Proliferation--drug effects Cell Survival--drug effects Dose-Response Relationship, Drug Drug Resistance, Multiple--drug effects Drug Resistance, Neoplasm--drug effects Drug Screening Assays, Antitumor Humans MCF-7 Cells Models, Molecular Molecular Structure Schiff Bases--chemistry Structure-Activity Relationship Thiosemicarbazones--chemistry Tumor Cells, Cultured