Wroblewski, M
Mast cells decrease efficacy of anti-angiogenic therapy by secreting matrix-degrading granzyme B. [electronic resource]
- Nature communications 08 2017
- 269 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
ISSN: 2041-1723
Standard No.: 10.1038/s41467-017-00327-8 doi
Subjects--Topical Terms: Angiogenesis Inhibitors--pharmacology Animals Anti-Asthmatic Agents--pharmacology Cell Line, Tumor Cell Proliferation--drug effects Cromolyn Sodium--pharmacology Endothelial Cells--drug effects Extracellular Matrix--drug effects Fibroblast Growth Factor 1--drug effects Fibroblast Growth Factor 2--drug effects Granulocyte-Macrophage Colony-Stimulating Factor--drug effects Granzymes--metabolism Human Umbilical Vein Endothelial Cells Laminin--metabolism Mast Cells--drug effects Mice Neoplasms--blood supply Neovascularization, Pathologic--metabolism Vascular Endothelial Growth Factor A--drug effects Vascular Endothelial Growth Factor Receptor-2--drug effects Vitronectin--metabolism