TY  - GEN
AU  - Poon,Edmund
AU  - Mullins,Stefanie
AU  - Watkins,Amanda
AU  - Williams,Geoffrey S
AU  - Koopmann,Jens-Oliver
AU  - Di Genova,Gianfranco
AU  - Cumberbatch,Marie
AU  - Veldman-Jones,Margaret
AU  - Grosskurth,Shaun E
AU  - Sah,Vasu
AU  - Schuller,Alwin
AU  - Reimer,Corrine
AU  - Dovedi,Simon J
AU  - Smith,Paul D
AU  - Stewart,Ross
AU  - Wilkinson,Robert W
TI  - The MEK inhibitor selumetinib complements CTLA-4 blockade by reprogramming the tumor immune microenvironment
SN  - 2051-1426
PY  - 2018///0521
KW  - Animals
KW  - Antibodies, Monoclonal
KW  - administration & dosage
KW  - Antibodies, Monoclonal, Humanized
KW  - Benzimidazoles
KW  - Biomarkers, Tumor
KW  - genetics
KW  - Cell Line, Tumor
KW  - Cellular Reprogramming
KW  - drug effects
KW  - Colorectal Neoplasms
KW  - drug therapy
KW  - Drug Synergism
KW  - Gene Expression Regulation, Neoplastic
KW  - Humans
KW  - Mice
KW  - Mutation
KW  - Proto-Oncogene Proteins p21(ras)
KW  - Tumor Microenvironment
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1186/s40425-017-0268-8
ER  -