TY  - GEN
AU  - Crompton,Michael
AU  - Purnell,Tom
AU  - Tyrer,Hayley E
AU  - Parker,Andrew
AU  - Ball,Greg
AU  - Hardisty-Hughes,Rachel E
AU  - Gale,Richard
AU  - Williams,Debbie
AU  - Dean,Charlotte H
AU  - Simon,Michelle M
AU  - Mallon,Ann-Marie
AU  - Wells,Sara
AU  - Bhutta,Mahmood F
AU  - Burton,Martin J
AU  - Tateossian,Hilda
AU  - Brown,Steve D M
TI  - A mutation in Nischarin causes otitis media via LIMK1 and NF-κB pathways
SN  - 1553-7404
PY  - 2017///0913
KW  - Alleles
KW  - Animals
KW  - Chromosome Mapping
KW  - Chronic Disease
KW  - Disease Models, Animal
KW  - Ear, Middle
KW  - metabolism
KW  - Ethylnitrosourea
KW  - toxicity
KW  - Female
KW  - Genotyping Techniques
KW  - Heterozygote
KW  - Homozygote
KW  - Humans
KW  - Imidazoline Receptors
KW  - Inflammation
KW  - genetics
KW  - Integrin alpha6
KW  - Intracellular Signaling Peptides and Proteins
KW  - Lim Kinases
KW  - Male
KW  - Mice
KW  - Mice, Knockout
KW  - Mutation, Missense
KW  - NF-kappa B
KW  - Neuropeptides
KW  - Otitis Media
KW  - Penetrance
KW  - Sequence Analysis, DNA
KW  - Up-Regulation
KW  - Vascular Endothelial Growth Factor A
KW  - p21-Activated Kinases
KW  - rac1 GTP-Binding Protein
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1371/journal.pgen.1006969
ER  -