TY  - GEN
AU  - Cairney,Claire J
AU  - Godwin,Lauren S
AU  - Bilsland,Alan E
AU  - Burns,Sharon
AU  - Stevenson,Katrina H
AU  - McGarry,Lynn
AU  - Revie,John
AU  - Moore,Jon D
AU  - Wiggins,Ceri M
AU  - Collinson,Rebecca S
AU  - Mudd,Clare
AU  - Tsonou,Elpida
AU  - Sadaie,Mahito
AU  - Bennett,Dorothy C
AU  - Narita,Masashi
AU  - Torrance,Christopher J
AU  - Keith,W Nicol
TI  - A 'synthetic-sickness' screen for senescence re-engagement targets in mutant cancer backgrounds
SN  - 1553-7404
PY  - 2017///0913
KW  - Caspase 3
KW  - genetics
KW  - Caspase 7
KW  - Cell Proliferation
KW  - Cellular Senescence
KW  - Cyclin-Dependent Kinase Inhibitor p21
KW  - Gene Expression Regulation, Neoplastic
KW  - Genetic Markers
KW  - HCT116 Cells
KW  - Humans
KW  - Melanoma
KW  - Mutation
KW  - Phosphatidylinositol 3-Kinases
KW  - RNA, Small Interfering
KW  - Reproducibility of Results
KW  - Tumor Suppressor Protein p53
KW  - Tumor Suppressor p53-Binding Protein 1
KW  - beta-Galactosidase
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1371/journal.pgen.1006942
ER  -