TY  - GEN
AU  - Janouskova,Hana
AU  - El Tekle,Geniver
AU  - Bellini,Elisa
AU  - Udeshi,Namrata D
AU  - Rinaldi,Anna
AU  - Ulbricht,Anna
AU  - Bernasocchi,Tiziano
AU  - Civenni,Gianluca
AU  - Losa,Marco
AU  - Svinkina,Tanya
AU  - Bielski,Craig M
AU  - Kryukov,Gregory V
AU  - Cascione,Luciano
AU  - Napoli,Sara
AU  - Enchev,Radoslav I
AU  - Mutch,David G
AU  - Carney,Michael E
AU  - Berchuck,Andrew
AU  - Winterhoff,Boris J N
AU  - Broaddus,Russell R
AU  - Schraml,Peter
AU  - Moch,Holger
AU  - Bertoni,Francesco
AU  - Catapano,Carlo V
AU  - Peter,Matthias
AU  - Carr,Steven A
AU  - Garraway,Levi A
AU  - Wild,Peter J
AU  - Theurillat,Jean-Philippe P
TI  - Opposing effects of cancer-type-specific SPOP mutants on BET protein degradation and sensitivity to BET inhibitors
SN  - 1546-170X
PY  - 2017///1002
KW  - Acetanilides
KW  - pharmacology
KW  - Adenocarcinoma, Clear Cell
KW  - genetics
KW  - Animals
KW  - Apoptosis
KW  - drug effects
KW  - Azepines
KW  - Carcinoma, Endometrioid
KW  - Carcinosarcoma
KW  - Cell Cycle Proteins
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Chromatography, Liquid
KW  - Cullin Proteins
KW  - metabolism
KW  - Drug Resistance, Neoplasm
KW  - Endometrial Neoplasms
KW  - Epigenesis, Genetic
KW  - Female
KW  - Heterocyclic Compounds, 3-Ring
KW  - Humans
KW  - Immunoblotting
KW  - Immunohistochemistry
KW  - Immunoprecipitation
KW  - Male
KW  - Mass Spectrometry
KW  - Mice, Nude
KW  - Molecular Targeted Therapy
KW  - Mutation
KW  - Neoplasm Transplantation
KW  - Neoplasms, Cystic, Mucinous, and Serous
KW  - Nuclear Proteins
KW  - antagonists & inhibitors
KW  - Prostatic Neoplasms
KW  - Protein Serine-Threonine Kinases
KW  - RNA-Binding Proteins
KW  - Repressor Proteins
KW  - Reverse Transcriptase Polymerase Chain Reaction
KW  - Transcription Factors
KW  - Triazoles
KW  - Ubiquitination
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1038/nm.4372
ER  -