TY - GEN AU - Liu,Chun-Yu AU - Huang,Tzu-Ting AU - Chu,Pei-Yi AU - Huang,Chun-Teng AU - Lee,Chia-Han AU - Wang,Wan-Lun AU - Lau,Ka-Yi AU - Tsai,Wen-Chun AU - Chao,Tzu-I AU - Su,Jung-Chen AU - Chen,Ming-Huang AU - Shiau,Chung-Wai AU - Tseng,Ling-Ming AU - Chen,Kuen-Feng TI - The tyrosine kinase inhibitor nintedanib activates SHP-1 and induces apoptosis in triple-negative breast cancer cells SN - 2092-6413 PY - 2018///0531 KW - Animals KW - Antineoplastic Agents KW - pharmacology KW - Apoptosis KW - drug effects KW - Cell Line, Tumor KW - Disease-Free Survival KW - Female KW - Gene Expression Regulation, Neoplastic KW - Humans KW - Indoles KW - Kaplan-Meier Estimate KW - Mice KW - Mice, Inbred BALB C KW - Protein Kinase Inhibitors KW - Protein Tyrosine Phosphatase, Non-Receptor Type 6 KW - genetics KW - Protein-Tyrosine Kinases KW - metabolism KW - RNA, Small Interfering KW - STAT3 Transcription Factor KW - Triple Negative Breast Neoplasms KW - drug therapy KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/emm.2017.114 ER -