Liu, Chun-Yu

The tyrosine kinase inhibitor nintedanib activates SHP-1 and induces apoptosis in triple-negative breast cancer cells. [electronic resource] - Experimental & molecular medicine 08 2017 - e366 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2092-6413

10.1038/emm.2017.114 doi


Animals
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Cell Line, Tumor
Disease-Free Survival
Female
Gene Expression Regulation, Neoplastic
Humans
Indoles--pharmacology
Kaplan-Meier Estimate
Mice
Mice, Inbred BALB C
Protein Kinase Inhibitors--pharmacology
Protein Tyrosine Phosphatase, Non-Receptor Type 6--genetics
Protein-Tyrosine Kinases--metabolism
RNA, Small Interfering--genetics
STAT3 Transcription Factor--genetics
Triple Negative Breast Neoplasms--drug therapy
Xenograft Model Antitumor Assays