3.3 Å structure of Niemann-Pick C1 protein reveals insights into the function of the C-terminal luminal domain in cholesterol transport. [electronic resource]
- Proceedings of the National Academy of Sciences of the United States of America 08 2017
- 9116-9121 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1091-6490
10.1073/pnas.1711716114 doi
Binding Sites--genetics Biological Transport--genetics Carrier Proteins--chemistry Cholesterol, LDL--metabolism Crystallography, X-Ray Cysteine--chemistry Endosomes--metabolism Humans Intracellular Signaling Peptides and Proteins Membrane Glycoproteins--chemistry Models, Molecular Mutation Niemann-Pick C1 Protein Niemann-Pick Disease, Type C--genetics Protein Domains