TY - GEN AU - Richard,Mathilde AU - Herfst,Sander AU - van den Brand,Judith M A AU - de Meulder,Dennis AU - Lexmond,Pascal AU - Bestebroer,Theo M AU - Fouchier,Ron A M TI - Mutations Driving Airborne Transmission of A/H5N1 Virus in Mammals Cause Substantial Attenuation in Chickens only when combined SN - 2045-2322 PY - 2019///0218 KW - Amino Acid Substitution KW - Animals KW - Cell Line KW - Chickens KW - virology KW - Influenza A Virus, H5N1 Subtype KW - genetics KW - Influenza in Birds KW - mortality KW - Mammals KW - Mutation KW - Orthomyxoviridae Infections KW - transmission KW - Phenotype KW - Respiratory Mucosa KW - pathology KW - Viral Load KW - Virus Replication KW - Virus Shedding N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/s41598-017-07000-6 ER -