TY - GEN AU - Ding,Xiao AU - Dai,Xuedong AU - Long,Kai AU - Peng,Cheng AU - Andreotti,Daniele AU - Bamborough,Paul AU - Eatherton,Andrew J AU - Edge,Colin AU - Jandu,Karamjit S AU - Nichols,Paula L AU - Philps,Oliver J AU - Stasi,Luigi Piero AU - Wan,Zehong AU - Xiang,Jia-Ning AU - Dong,Kelly AU - Dossang,Pamela AU - Ho,Ming-Hsun AU - Li,Yi AU - Mensah,Lucy AU - Guan,Xiaoming AU - Reith,Alastair D AU - Ren,Feng TI - Discovery of 5-substituent-N-arylbenzamide derivatives as potent, selective and orally bioavailable LRRK2 inhibitors SN - 1464-3405 PY - 2017///0908 KW - Administration, Oral KW - Benzamides KW - administration & dosage KW - Dose-Response Relationship, Drug KW - Drug Discovery KW - Humans KW - Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 KW - antagonists & inhibitors KW - Molecular Structure KW - Protein Kinase Inhibitors KW - Structure-Activity Relationship N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.bmcl.2017.07.052 ER -