Mahmoud, Ayman M <br/><br/>
Berberine ameliorates methotrexate-induced liver injury by activating Nrf2/HO-1 pathway and PPARγ, and suppressing oxidative stress and apoptosis in rats.  [electronic resource] 

 -  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie  Oct 2017 
 - 280-291 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1950-6007 
<br/><br/><label>Standard No.: </label>10.1016/j.biopha.2017.07.101  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Apoptosis--drug effects<br/>Berberine--therapeutic use<br/>Chemical and Drug Induced Liver Injury--metabolism<br/>Heme Oxygenase (Decyclizing)--metabolism<br/>Male<br/>Methotrexate--toxicity<br/>NF-E2-Related Factor 2--metabolism<br/>Oxidative Stress--drug effects<br/>PPAR gamma--metabolism<br/>Rats, Wistar<br/>Signal Transduction