TY - GEN AU - Li,Wennan AU - Chen,Xingjuan AU - Riley,Ashley M AU - Hiett,S Christopher AU - Temm,Constance J AU - Beli,Eleni AU - Long,Xin AU - Chakraborty,Saikat AU - Alloosh,Mouhamad AU - White,Fletcher A AU - Grant,Maria B AU - Sturek,Michael AU - Obukhov,Alexander G TI - Long-term spironolactone treatment reduces coronary TRPC expression, vasoconstriction, and atherosclerosis in metabolic syndrome pigs SN - 1435-1803 PY - 2018///0521 KW - Animals KW - Calcium Signaling KW - drug effects KW - Cells, Cultured KW - Coronary Artery Disease KW - genetics KW - Coronary Vessels KW - Disease Models, Animal KW - Down-Regulation KW - Drug Administration Schedule KW - Endothelium, Vascular KW - Macrophages KW - Metabolic Syndrome KW - drug therapy KW - Mineralocorticoid Receptor Antagonists KW - administration & dosage KW - Muscle, Smooth, Vascular KW - Spironolactone KW - Swine KW - Swine, Miniature KW - TRPC Cation Channels KW - TRPC6 Cation Channel KW - Time Factors KW - Tissue Culture Techniques KW - Vasoconstriction N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1007/s00395-017-0643-0 ER -