Yamaguchi, Kiyoshi

Bidirectional reporter assay using HAL promoter and TOPFLASH improves specificity in high-throughput screening of Wnt inhibitors. [electronic resource] - Biotechnology and bioengineering 12 2017 - 2868-2882 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1097-0290

10.1002/bit.26394 doi


Biological Assay
Brefeldin A--administration & dosage
Drug Design
Drug Evaluation, Preclinical--methods
Genes, Reporter--genetics
High-Throughput Screening Assays--methods
Histidine Ammonia-Lyase--genetics
Promoter Regions, Genetic--genetics
Wnt Proteins--antagonists & inhibitors
Wnt Signaling Pathway--drug effects