Zhou, Li-Yun

Design, synthesis and biological evaluation of dual acetylcholinesterase and phosphodiesterase 5A inhibitors in treatment for Alzheimer's disease. [electronic resource] - Bioorganic & medicinal chemistry letters 09 2017 - 4180-4184 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1464-3405

10.1016/j.bmcl.2017.07.013 doi


Acetylcholinesterase--metabolism
Alzheimer Disease--drug therapy
Cell Line, Tumor
Cell Survival--drug effects
Cholinesterase Inhibitors--chemical synthesis
Cyclic Nucleotide Phosphodiesterases, Type 5--metabolism
Dose-Response Relationship, Drug
Drug Design
Humans
Molecular Structure
Phosphodiesterase Inhibitors--chemistry
Structure-Activity Relationship