Sarin, Navin
Cisplatin resistance in non-small cell lung cancer cells is associated with an abrogation of cisplatin-induced G2/M cell cycle arrest. [electronic resource]
- PloS one 2017
- e0181081 p. digital
Publication Type: Journal Article
ISSN: 1932-6203
Standard No.: 10.1371/journal.pone.0181081 doi
Subjects--Topical Terms: A549 Cells Antineoplastic Agents--pharmacology Apoptosis--drug effects Ataxia Telangiectasia Mutated Proteins--genetics Blotting, Western Carcinoma, Non-Small-Cell Lung--genetics Carrier Proteins--genetics Cisplatin--pharmacology Cyclin-Dependent Kinase Inhibitor p21--genetics DNA-Binding Proteins--genetics Drug Resistance, Neoplasm--drug effects G2 Phase Cell Cycle Checkpoints--drug effects Gene Expression Regulation, Neoplastic--drug effects Heat-Shock Proteins--genetics Humans Lung Neoplasms--genetics Proto-Oncogene Proteins c-mdm2--genetics Reverse Transcriptase Polymerase Chain Reaction Tumor Suppressor Protein p53--genetics