TY - GEN AU - Xu,Jiayue AU - Boström,Adrian E AU - Saeed,Mohamed AU - Dubey,Raghvendra K AU - Waeber,Gérard AU - Vollenweider,Peter AU - Marques-Vidal,Pedro AU - Mwinyi,Jessica AU - Schiöth,Helgi B TI - A genetic variant in the catechol-O-methyl transferase (COMT) gene is related to age-dependent differences in the therapeutic effect of calcium-channel blockers SN - 1536-5964 PY - 2017///0814 KW - Age Factors KW - Aged KW - Aged, 80 and over KW - Aging KW - drug effects KW - Antihypertensive Agents KW - therapeutic use KW - Aromatase KW - genetics KW - Blood Pressure KW - Calcium Channel Blockers KW - Catechol O-Methyltransferase KW - Cohort Studies KW - Female KW - Genotyping Techniques KW - Glucuronosyltransferase KW - Humans KW - Male KW - Middle Aged KW - Pharmacogenomic Variants KW - Switzerland N1 - Publication Type: Journal Article UR - https://doi.org/10.1097/MD.0000000000007029 ER -