A genetic variant in the catechol-O-methyl transferase (COMT) gene is related to age-dependent differences in the therapeutic effect of calcium-channel blockers. [electronic resource]
- Medicine Jul 2017
- e7029 p. digital
Publication Type: Journal Article
1536-5964
10.1097/MD.0000000000007029 doi
Age Factors Aged Aged, 80 and over Aging--drug effects Antihypertensive Agents--therapeutic use Aromatase--genetics Blood Pressure--drug effects Calcium Channel Blockers--therapeutic use Catechol O-Methyltransferase--genetics Cohort Studies Female Genotyping Techniques Glucuronosyltransferase--genetics Humans Male Middle Aged Pharmacogenomic Variants Switzerland