TY  - GEN
AU  - Zhang,Guo-Hai
AU  - Yuan,Jing-Mei
AU  - Qian,Gang
AU  - Gu,Chen-Xi
AU  - Wei,Kai
AU  - Mo,Dong-Liang
AU  - Qin,Jiang-Ke
AU  - Peng,Yan
AU  - Zhou,Zu-Ping
AU  - Pan,Cheng-Xue
AU  - Su,Gui-Fa
TI  - Phthalazino[1,2-b]quinazolinones as p53 Activators: Cell Cycle Arrest, Apoptotic Response and Bak-Bcl-xl Complex Reorganization in Bladder Cancer Cells
SN  - 1520-4804
PY  - 2017///0926
KW  - Antineoplastic Agents
KW  - chemical synthesis
KW  - Apoptosis
KW  - drug effects
KW  - Camptothecin
KW  - analogs & derivatives
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Drug Screening Assays, Antitumor
KW  - G2 Phase Cell Cycle Checkpoints
KW  - Humans
KW  - Phthalazines
KW  - Quinazolinones
KW  - S Phase Cell Cycle Checkpoints
KW  - Tumor Suppressor Protein p53
KW  - metabolism
KW  - Urinary Bladder Neoplasms
KW  - bcl-2 Homologous Antagonist-Killer Protein
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1021/acs.jmedchem.6b01769
ER  -