Zhang, Guo-Hai <br/><br/>
Phthalazino[1,2-b]quinazolinones as p53 Activators: Cell Cycle Arrest, Apoptotic Response and Bak-Bcl-xl Complex Reorganization in Bladder Cancer Cells.  [electronic resource] 

 -  Journal of medicinal chemistry  08 2017 
 - 6853-6866 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/acs.jmedchem.6b01769  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents--chemical synthesis<br/>Apoptosis--drug effects<br/>Camptothecin--analogs & derivatives<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Drug Screening Assays, Antitumor<br/>G2 Phase Cell Cycle Checkpoints--drug effects<br/>Humans<br/>Phthalazines--chemical synthesis<br/>Quinazolinones--chemical synthesis<br/>S Phase Cell Cycle Checkpoints--drug effects<br/>Tumor Suppressor Protein p53--metabolism<br/>Urinary Bladder Neoplasms--metabolism<br/>bcl-2 Homologous Antagonist-Killer Protein--metabolism