TY - GEN AU - Do,Bich Hang AU - Kang,Hyo Jeong AU - Song,Jung-A AU - Nguyen,Minh Tan AU - Park,Sangsu AU - Yoo,Jiwon AU - Nguyen,Anh Ngoc AU - Kwon,Grace G AU - Jang,Jaepyeong AU - Jang,Mihee AU - Lee,Sunju AU - So,Seoungjun AU - Sim,Seongrak AU - Lee,Kyung Jin AU - Osborn,Mark J AU - Choe,Han TI - Granulocyte colony-stimulating factor (GCSF) fused with Fc Domain produced from E. coli is less effective than Polyethylene Glycol-conjugated GCSF SN - 2045-2322 PY - 2019///0204 KW - Animals KW - Cell Line KW - Cell Proliferation KW - drug effects KW - Escherichia coli KW - genetics KW - Granulocyte Colony-Stimulating Factor KW - Humans KW - Hydrogen-Ion Concentration KW - Immunoglobulin Fc Fragments KW - Neutropenia KW - drug therapy KW - Polyethylene Glycols KW - chemistry KW - Protein Engineering KW - methods KW - Rats, Sprague-Dawley KW - Recombinant Proteins N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/s41598-017-06726-7 ER -