TY - GEN AU - Zhang,Zhixin AU - Lu,Fang AU - Liu,Haiyu AU - Zhao,Huizhen AU - Liu,Yuehong AU - Fu,Shuang AU - Wang,Meiling AU - Xie,Ziye AU - Yu,Honghong AU - Huang,Zhenghai AU - Zhang,Yanling AU - Gao,Xiaoyan TI - An integrated strategy by using target tissue metabolomics biomarkers as pharmacodynamic surrogate indices to screen antipyretic components of Qingkaikling injection SN - 2045-2322 PY - 2019///0225 KW - Administration, Intravenous KW - Animals KW - Antipyretics KW - administration & dosage KW - Drugs, Chinese Herbal KW - chemistry KW - Flavonoids KW - analysis KW - Hypothalamus KW - Iridoids KW - Male KW - Medicine, Chinese Traditional KW - Metabolomics KW - methods KW - Rats KW - Rats, Sprague-Dawley N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/s41598-017-05812-0 ER -