Hiruma, Yoshitaka <br/><br/>
Understanding inhibitor resistance in Mps1 kinase through novel biophysical assays and structures.  [electronic resource] 

 -  The Journal of biological chemistry  09 2017 
 - 14496-14504 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article 
<br/><br/><label>ISSN: </label>1083-351X 
<br/><br/><label>Standard No.: </label>10.1074/jbc.M117.783555  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adenosine Triphosphate--chemistry<br/>Amino Acid Substitution<br/>Antineoplastic Agents--chemistry<br/>Binding Sites<br/>Catalytic Domain<br/>Cell Cycle Proteins--antagonists & inhibitors<br/>Crystallography, X-Ray<br/>Humans<br/>Kinetics<br/>Ligands<br/>Models, Molecular<br/>Molecular Structure<br/>Morpholines--chemistry<br/>Phosphorylation--drug effects<br/>Point Mutation<br/>Protein Kinase Inhibitors--chemistry<br/>Protein Processing, Post-Translational--drug effects<br/>Protein Serine-Threonine Kinases--antagonists & inhibitors<br/>Protein-Tyrosine Kinases--antagonists & inhibitors<br/>Purines--chemistry<br/>Pyrazoles--chemistry<br/>Quinazolines--chemistry<br/>Recombinant Fusion Proteins--chemistry<br/>Recombinant Proteins--chemistry