TY - GEN AU - St Pierre,Cristina AU - Guo,Jane AU - Shin,John D AU - Engstrom,Laura W AU - Lee,Hyun-Hee AU - Herbert,Alan AU - Surdi,Laura AU - Baker,James AU - Salmon,Michael AU - Shah,Sanjiv AU - Ellis,J Michael AU - Houshyar,Hani AU - Crackower,Michael A AU - Kleinschek,Melanie A AU - Jones,Dallas C AU - Hicks,Alexandra AU - Zaller,Dennis M AU - Alves,Stephen E AU - Ramadas,Ravisankar A TI - A human tissue-based functional assay platform to evaluate the immune function impact of small molecule inhibitors that target the immune system SN - 1932-6203 PY - 2017///0927 KW - Chemokines KW - biosynthesis KW - Drug Evaluation, Preclinical KW - methods KW - Humans KW - Immune System KW - cytology KW - Killer Cells, Natural KW - drug effects KW - Leukocytes, Mononuclear KW - Phagocytes KW - Reactive Oxygen Species KW - metabolism KW - Small Molecule Libraries KW - pharmacology KW - T-Lymphocytes KW - Toll-Like Receptors KW - Transcriptome N1 - Publication Type: Journal Article UR - https://doi.org/10.1371/journal.pone.0180870 ER -