St Pierre, Cristina A human tissue-based functional assay platform to evaluate the immune function impact of small molecule inhibitors that target the immune system. [electronic resource] - PloS one 2017 - e0180870 p. digital Publication Type: Journal Article ISSN: 1932-6203 Standard No.: 10.1371/journal.pone.0180870 doi Subjects--Topical Terms: Chemokines--biosynthesisDrug Evaluation, Preclinical--methodsHumansImmune System--cytologyKiller Cells, Natural--drug effectsLeukocytes, Mononuclear--drug effectsPhagocytes--drug effectsReactive Oxygen Species--metabolismSmall Molecule Libraries--pharmacologyT-Lymphocytes--drug effectsToll-Like Receptors--metabolismTranscriptome--drug effects