TY - GEN AU - Bothe,Melanie K AU - Maathuis,Annet J H AU - Bellmann,Susann AU - van der Vossen,Jos M B M AU - Berressem,Dirk AU - Koehler,Annalena AU - Schwejda-Guettes,Susann AU - Gaigg,Barbara AU - Kuchinka-Koch,Angelika AU - Stover,John F TI - Dose-Dependent Prebiotic Effect of Lactulose in a Computer-Controlled In Vitro Model of the Human Large Intestine SN - 2072-6643 PY - 2018///0510 KW - Acetates KW - metabolism KW - Adult KW - Ammonia KW - Bifidobacterium KW - drug effects KW - Body Mass Index KW - Butyrates KW - Computer Simulation KW - DNA, Bacterial KW - isolation & purification KW - Dose-Response Relationship, Drug KW - Fatty Acids, Volatile KW - Female KW - Gastrointestinal Microbiome KW - Humans KW - Hydrogen-Ion Concentration KW - Intestine, Large KW - Lactic Acid KW - Lactobacillus KW - Lactulose KW - administration & dosage KW - Male KW - Models, Biological KW - Prebiotics KW - RNA, Ribosomal, 16S KW - Sequence Analysis, DNA N1 - Publication Type: Journal Article UR - https://doi.org/10.3390/nu9070767 ER -