Kawamoto, Taisuke <br/><br/>
Mechanism-based risk assessment strategy for drug-induced cholestasis using the transcriptional benchmark dose derived by toxicogenomics.  [electronic resource] 

 -  The Journal of toxicological sciences  2017 
 - 427-436 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1880-3989 
<br/><br/><label>Standard No.: </label>10.2131/jts.42.427  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Administration, Oral<br/>Animals<br/>Chlorpromazine--administration & dosage<br/>Cholestasis--chemically induced<br/>Cholesterol--biosynthesis<br/>Cyclosporine--administration & dosage<br/>Diclofenac--administration & dosage<br/>Dose-Response Relationship, Drug<br/>Flutamide--administration & dosage<br/>Gene Expression<br/>Humans<br/>Imipramine--administration & dosage<br/>Inflammation--genetics<br/>Ketoconazole--administration & dosage<br/>Liver<br/>Methyltestosterone--administration & dosage<br/>Oxidative Stress--genetics<br/>Rats<br/>Risk Assessment--methods<br/>Sulindac--administration & dosage<br/>Tamoxifen--administration & dosage<br/>Toxicogenetics--methods