Gao, Hongying

Synthesis and evaluation of osimertinib derivatives as potent EGFR inhibitors. [electronic resource] - Bioorganic & medicinal chemistry 09 2017 - 4553-4559 p. digital

Publication Type: Journal Article

1464-3391

10.1016/j.bmc.2017.06.004 doi


Acrylamides--chemical synthesis
Aniline Compounds
Animals
Antineoplastic Agents--chemical synthesis
Cell Line, Tumor
Cell Proliferation--drug effects
Drug Design
ErbB Receptors--antagonists & inhibitors
Female
Humans
Mice
Mice, Nude
Mutation
Neoplasms--drug therapy
Phenylenediamines--chemical synthesis
Piperazines--chemistry
Protein Kinase Inhibitors--chemical synthesis
Signal Transduction--drug effects
Transplantation, Heterologous