Gao, Hongying
Synthesis and evaluation of osimertinib derivatives as potent EGFR inhibitors. [electronic resource]
- Bioorganic & medicinal chemistry 09 2017
- 4553-4559 p. digital
Publication Type: Journal Article
ISSN: 1464-3391
Standard No.: 10.1016/j.bmc.2017.06.004 doi
Subjects--Topical Terms: Acrylamides--chemical synthesis Aniline Compounds Animals Antineoplastic Agents--chemical synthesis Cell Line, Tumor Cell Proliferation--drug effects Drug Design ErbB Receptors--antagonists & inhibitors Female Humans Mice Mice, Nude Mutation Neoplasms--drug therapy Phenylenediamines--chemical synthesis Piperazines--chemistry Protein Kinase Inhibitors--chemical synthesis Signal Transduction--drug effects Transplantation, Heterologous