Predictors of Hand-Foot Syndrome and Pyridoxine for Prevention of Capecitabine-Induced Hand-Foot Syndrome: A Randomized Clinical Trial. [electronic resource]
- JAMA oncology Nov 2017
- 1538-1545 p. digital
Adult Aged Aged, 80 and over Antimetabolites, Antineoplastic--adverse effects Asian People--genetics Capecitabine--adverse effects Chi-Square Distribution Dihydrouracil Dehydrogenase (NADP)--genetics Double-Blind Method Drug Administration Schedule Female Folic Acid--blood Genetic Predisposition to Disease Genome-Wide Association Study Hand-Foot Syndrome--blood Humans Incidence Intracellular Signaling Peptides and Proteins--genetics Kaplan-Meier Estimate Logistic Models Male Membrane Proteins--genetics Microfilament Proteins--genetics Middle Aged Multivariate Analysis Neoplasms--blood Odds Ratio Pharmacogenomic Variants Polymorphism, Single Nucleotide Predictive Value of Tests Pyridoxine--administration & dosage Risk Assessment Risk Factors Severity of Illness Index Singapore--epidemiology Time Factors Treatment Outcome