TY - GEN AU - Liu,Pu-Ste AU - Wang,Haiping AU - Li,Xiaoyun AU - Chao,Tung AU - Teav,Tony AU - Christen,Stefan AU - Di Conza,Giusy AU - Cheng,Wan-Chen AU - Chou,Chih-Hung AU - Vavakova,Magdalena AU - Muret,Charlotte AU - Debackere,Koen AU - Mazzone,Massimiliano AU - Huang,Hsien-Da AU - Fendt,Sarah-Maria AU - Ivanisevic,Julijana AU - Ho,Ping-Chih TI - α-ketoglutarate orchestrates macrophage activation through metabolic and epigenetic reprogramming SN - 1529-2916 PY - 2017///0911 KW - Animals KW - Cellular Reprogramming KW - immunology KW - Chromatin Immunoprecipitation KW - Citric Acid Cycle KW - Epigenesis, Genetic KW - Fatty Acids KW - metabolism KW - Gene Expression Profiling KW - Glutamine KW - Glycolysis KW - Ketoglutaric Acids KW - Lipopolysaccharides KW - Macrophage Activation KW - Macrophages KW - Metabolomics KW - Mice KW - NF-kappa B KW - Oxidation-Reduction KW - Oxidative Phosphorylation KW - Phenotype KW - Reverse Transcriptase Polymerase Chain Reaction KW - Sequence Analysis, RNA KW - Succinic Acid N1 - Publication Type: Journal Article UR - https://doi.org/10.1038/ni.3796 ER -