TY  - GEN
AU  - Wang,Yu-Qing
AU  - Huang,Zhou-Li
AU  - Chen,Shuo-Bin
AU  - Wang,Chen-Xi
AU  - Shan,Chan
AU  - Yin,Qi-Kun
AU  - Ou,Tian-Miao
AU  - Li,Ding
AU  - Gu,Lian-Quan
AU  - Tan,Jia-Heng
AU  - Huang,Zhi-Shu
TI  - Design, Synthesis, and Evaluation of New Selective NM23-H2 Binders as c-MYC Transcription Inhibitors via Disruption of the NM23-H2/G-Quadruplex Interaction
SN  - 1520-4804
PY  - 2017///0926
KW  - Animals
KW  - Antineoplastic Agents
KW  - administration & dosage
KW  - Apoptosis
KW  - drug effects
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Down-Regulation
KW  - Doxorubicin
KW  - pharmacology
KW  - Drug Design
KW  - G-Quadruplexes
KW  - G1 Phase Cell Cycle Checkpoints
KW  - Humans
KW  - Ligands
KW  - Mice, Inbred BALB C
KW  - Molecular Docking Simulation
KW  - NM23 Nucleoside Diphosphate Kinases
KW  - antagonists & inhibitors
KW  - Promoter Regions, Genetic
KW  - Proto-Oncogene Proteins c-myc
KW  - Pyrroles
KW  - Quinazolines
KW  - Quinazolinones
KW  - Structure-Activity Relationship
KW  - Transcription, Genetic
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1021/acs.jmedchem.7b00421
ER  -